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Symptoms may manifest as muscle weakness, cardiomyopathy, hypoglycemic coma, and abnormal liver function

In this context, fibroblast growth factor 21 (FGF21) analogues are attractive because they target multiple components of MASH biology simultaneously, with potential to improve steatosis, inflammation, fibrosis, and broader cardiometabolic risk

Participants reported changes in food preferences toward healthier choices and improved relationship with food

Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels

Combining both interventions might intensify these effects, potentially affecting treatment adherence and quality of life

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